Prednisolone Nycomed is a man-made glucocorticosteroid pharmaceutical product or a dehydrated analog of hydrocortisone. Basically, it has anti-inflammatory, anti-allergic and immunosuppressive effects, and its use increases the sensitivity of beta-adrenergic receptors to endogenous catecholamines. This medication interacts with specific cytoplasmic receptors (glucocorticosteroid receptors (GCS) are present in all tissues, especially in the liver) to form a complex that induces the formation of proteins, including the enzymes that regulate vital processes in cells. Prednisolone international names include Orapred, Pediapred, Prelone and some others.
What Prednisolone Is Prescribed For
Nowadays, this medication is prescribed by doctors to their patients to achieve fast suppression of the inflammation caused by specific allergic, inflammatory and other conditions, including:
- Ulcerative colitis, systemic lupus, psoriatic arthritis and others;
- Some severe allergic conditions that don’t respond to standard treatment option can be cured by Prednisolone, including atopic dermatitis, bronchial asthma and hay fever;
- Chronic inflammatory and allergic conditions of the iris, uvea, optic nerves and conjunctiva;
- Chronic skin conditions, such as severe psoriasis, pemphigus, etc.
Besides, Prednisolone is often taken by patients to treat such diseases as:
- Sarcoidosis and thyroiditis;
- Lymphomas and leukemias;
- Blood conditions that involve the destruction of immune and red blood cells.
Sometimes, this medicine is used as effective hormone replacement by those patients whose adrenal grands can’t produce enough corticosteroids.
Basic Guidelines on How to Take Prednisolone Correctly
Prednisolone 20 mg should be taken orally, with milk or food to prevent upset stomach. In general, the length of this treatment and your regular dosage are based on a particular medical condition and individual response, so only qualified doctors can prescribe it. Some patients take this medicine up to 4 times a day, while others take it only once a day. It’s not allowed to change your dose or stop taking Prednisolone without consulting your physician, because your condition may get worse. Your dosage must be reduced gradually to avoid sudden health complications, because this medication may cause specific withdrawal symptoms if you stop using it suddenly, especially when it comes to high doses and long-lasting treatment plans. These symptoms include muscle pain, weakness, nausea, headaches, dizziness, weight loss, tiredness and others.
List of Possible Prednisolone Side Effects
Some patients may develop side effects when using this medicine, including dizziness, headaches, heartburn, trouble sleeping, sweating, etc. Most of them are mild, and if they get worse, you need to call your doctor at once. Most of those people who take Prednisolone don’t have any unwanted symptoms. It works by weakening your immune system, so its intake may decrease the ability to fight different infections, thus, making you more sensitive to them. When you notice any new signs of infections, such as coughing, chills, fever and others, you need to go to the hospital immediately. Prolonged use of Prednisolone may result in yeast infection or oral thrush. For diabetics, you need to check your blood sugar levels on a regular basis when taking this medication. Check Prednisolone wiki to get a full list of possible adverse effects and inform your doctor once you develop such unlikely severe side effects as:
- Sudden vision problems and feet swelling;
- Unusual tiredness and weight gain;
- Easy bleeding and bruising;
- Mood and mental changes;
- Thinning skin and puffy face;
- Sudden hair growth and muscle weakness or pain;
- Bone pain and persistent stomach pain;
- Bloody and black stools;
- Seizures and chest pain;
- Serious allergic reactions.
Important Precautions when Undergoing This Treatment
Before using Prednisolone, let your doctor know about such pre-existing conditions as allergies, heart problems, eye diseases, liver and kidney ailments, hypertension, diabetes, thyroid complications, osteoporosis, bleeding issues, mood and mental changes, stomach conditions, seizures and others. In addition, you shouldn’t combine Prednisolone with specific medications, including other pills that weaken your immune system, blood thinners, NSAIDs, azole antifungals, drugs that lead to bleeding and so on.